Jan Stegemann, Ph.D.

Professor Stegemann’s research laboratory focuses on the use of extracellular environments to control cell function and promote tissue regeneration. The group’s work involves characterizing how cells interact with the 3D environment that surrounds them in native tissues, including the extracellular matrix, soluble biochemicals, and mechanical forces. The lab then uses this knowledge to create composite materials using proteins, polysaccharides, and synthetic polymers to direct cell function and to deliver cells for therapeutic purposes. Current application areas are in enhancing bone regeneration through cell therapy, and the development of multiphase engineered tissues that promote both bone and blood vessel formation. The lab also uses advanced imaging techniques to study mechanobiology and to characterize the mechanical properties of soft biomaterials.

Research Areas:

Artificial Organs, Bio-Nanotechnology, Biomaterials, Biomechanics, Cardiovascular, Engineering Education, Organ and Whole Body Biomechanics, Skeletal Orthopaedics, Tissue Engineering and Biomaterials, Tissue Engineering and Regenerative Medicine

• BME MEng Program Director

he/him/his

• Biomedical Product Realization Practicum
• Quality Systems, Risk Management, and Regulatory Structures
• Advanced Medical Product Development
• Graduate Innovative Design in Biomedical Engineering
• Biology and Engineering of the Extracellular Matrix
• Tissue-Biomaterial Interactions

Selected professional service activities in the past 5 years:

• MichBio Workforce and Education Committee, Member (part of state-wide MichBio industry advocacy organization)
• Chair, Publications Committee (responsible for contract negotiations with journal publisher, and oversight of all Society publications), Society for Biomaterials
• Academic Advisory Committee, Dept. of Biomedical Engineering, Shantou University, Shantou, China
• Chair, Education & Professional Development Committee, Society for Biomaterials
• US-FDA Federal Advisory Committee (FACA) on Cellular, Tissue, and Gene Therapies (CTGT)
• Affiliations Committee (identifies outside groups and organizations for partner initiatives) of the national Biomedical Engineering Society (BMES)
• Elected to the Council of the Tissue Engineering and Regenerative Medicine International Society – Americas chapter (TERMIS-AM)
• Publications Committee (advises Society journal on issues of production and distribution of technical and other literature), Society for Biomaterials
• Chair, External Affairs Committee, Tissue Engineering and Regenerative Medicine International Society – Americas chapter (TERMIS-AM)
• Endorsements Committee, Tissue Engineering and Regenerative Medicine International Society – Americas chapter (TERMIS-AM)

Jan Stegemann is a Professor of Biomedical Engineering and Director of the Advanced Medical Product Engineering and Development (AMPED) program at the University of Michigan. His research interests are in the areas of biomaterials and cell-based therapies for cardiovascular and orthopaedic applications. His teaching activities are mainly in the areas of biomaterials, tissue engineering, and medical product development. In addition to his current roles, Dr. Stegemann has served as Associate Chair for Master’s Programs and Associate Chair for Undergraduate Education in the Biomedical Engineering Department and has served on numerous faculty recruiting, curriculum development, and departmental planning committees. He is a member of the Advisory Board of the Bioengineering Program at UM-Dearborn and serves on a number of government panels, including the FDA Advisory Committee (FACA) on Cellular, Tissue, and Gene Therapy. He holds leadership positions in several professional societies and is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), a fellow of the Biomedical Engineering Society (BMES), and a Fellow of Biomaterial Science and Engineering (SFB). He received BS and MS degrees in Chemical Engineering from the University of Toronto, and a PhD in Biomedical Engineering from the Georgia Institute of Technology.

Selected awards in the past 10 years:

• Fellow, American Institute for Medical and Biological Engineering (AIMBE)
• Fellow, Biomedical Engineering Society (BMES)
• Fellow, Biomaterials Science and Engineering (Society for Biomaterials)
• Fellow, Interprofessional Education Leadership Program, U-M
• Otto Mønsted Visiting Professorship, Technical University of Denmark
• Monroe-Brown Foundation Service Excellence Award, U-M
• College of Engineering Recognition for Creativity & Innovation, U-M
• Gastprofessor Visiting Professorship (German Research Foundation)