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Biography
Chima Maduka’s journey into science began as a small animal veterinarian, a role he enjoyed for several years. This hands-on experience in medicine laid the foundation for his later work.
A graduate fellowship from the Mastercard Foundation brought him to Michigan State University (MSU) for his Master’s degree, where he studied brachycephalic airway syndrome in dogs, a condition similar to sleep apnea in humans. It was during a research stint in Orthopedic Surgery at the University of Michigan, as a Mastercard scholar, that he found his true passion. His work, surgically implanting ceramic biomaterials in craniofacial defects, sparked a keen interest at the intersection of materials and biomedical engineering.
This new focus led him back to MSU, where he pursued a PhD focused on tissue engineering. His doctoral research uncovered the immunometabolic basis of chronic inflammation in response to commonly used biomaterials. Following his PhD, Chima completed postdoctoral training at the BioFrontiers Institute (Chemical & Biological Engineering) in the University of Colorado Boulder, where he focused on drug delivery to the diseased heart. In this role, he developed various drug delivery platforms, including targeted, enzyme-responsive nanomaterials to treat heart failure after a heart attack, supported by an American Heart Association postdoctoral fellowship.
As a clinician-scientist, Chima is deeply passionate about bridging the gap between medicine and engineering. As an Michigan Program for Advancing Cultural Transformation (M-PACT) scholar, he is dedicated to fostering inclusive excellence in the field through his research, mentorship, teaching, and service.
Education
- Postdoctoral Fellow, BioFrontiers Institute/Chemical and Biological Engineering, University of Colorado, Boulder
- MS and PhD, Comparative Medicine and Integrative Biology (Surgery & Tissue Engineering), Michigan State University
- DVM, University of Maiduguri; Maiduguri, Nigeria.
Research Interests
Cardiac tissue engineering, biomaterials, immunometabolism, drug delivery for
precision health, Micro-Nanotechnology & Molecular Engineering, Immunoengineering and Regenerative Medicine
Our long-term goal is to elucidate and control the immunometabolic dependencies of chronic diseases using biomaterials. We explore stromal cell contribution to chronic inflammation in post-myocardial infarction and obesity-associated heart failure to inform new drug delivery platforms by leveraging biocompatible polymers. This highly multidisciplinary approach equips trainees with expertise in translational medicine, enabling them to bridge basic science findings to clinical applications.
Additional Title
- Scholar, Michigan Program for Advancing Cultural Transformation in the Biomedical Health Sciences
Awards
- American Heart Association Postdoctoral Fellowship 2024-2025
- METiS Therapeutics Travel Award for the Society for Biomaterials 2024
- Society for Biomaterials Postdoctoral Recognition Award (Honorable Mention) 2023
- Orthopedic Research Society Student/ Trainee Award 2021
- Mastercard Foundation Scholarship (Graduate Fellowship) 2017-2019
- Late Dr. (Mrs.) Elizabeth Gadzama’s & Dr. Hamisu Yelwa’s memorial prizes for the overall best graduating student, College of Veterinary Medicine.
