Xueding Wang, Ph.D.

Dr. Wang’s research group, Optical Imaging Laboratory at the U-M School of Medicine, is focused on imaging and therapeutic system development, and adaptation of novel diagnostic and therapeutic technologies to laboratory research and clinical settings, especially those involving light and ultrasound. One of our research interests is the development and clinical applications of photoacoustic imaging, including those involving breast cancer, inflammatory arthritis, prostate cancer, liver conditions, bowel disease, eye conditions, and brain disorders. Another research topic is the development of a novel therapeutic technology synergistically involving both light and ultrasound, namely photo-mediated ultrasound therapy. Our lab is also developing ionizing radiation acoustic imaging (iRAI) technology which provides a promising solution to map radiation dose distribution in the deep human body during radiation therapy.

Research Areas:

Biomedical Imaging, Biomedical Optics, Biomedical Ultrasonics and Image-Guided Therapy, Cancer, Neurological Disorders, Skeletal Orthopaedics

• Department of Radiology
• Director, Optical Imaging Laboratory

• BME 350

• 2002: Optical Society of America (OSA)
• 2003: Member of American Association of Physicists in Medicine (AAPM)
• 2004: Member of International Society for Optical Engineering (SPIE)
• 2005: Member of American Institute of Ultrasound in Medicine (AIUM)
• 2013: Senior Member of IEEE
• 2014: IEEE UFFC-S Representative to the Journal of Lightwave Technology

• V. P. Nguyen, J. Henry, J. Zhe, J. Hu, X. Wang, and Y. M. Paulus, “Multimodal imaging of laser-induced choroidal neovascularization in pigmented rabbits,” Scientific Reports 13(1): 3896 (2023).
• X. Peng, Z. Xu, A. Dentinger, S. Kewalramani, J. Jo, G. Xu, D. Chamberland, N. Abdulaziz, G. Gandikota, D. Mills, and X. Wang, “Longitudinal volumetric assessment of inflammatory arthritis via photoacoustic imaging and Doppler ultrasound imaging,” Photoacoustics 31:100514 (2023).
• V. P. Nguyen, W. Qian, J. Zhe, J. Henry, M. Wang, B. Liu, W. Zhang, X. Wang, and Y. M. Paulus, “Renally Clearable Ultraminiature Chain-Like Gold Nanoparticle Clusters for Multimodal Molecular Imaging of Choroidal Neovascularization,” Advanced Materials 35(31): e2302069 (2023).
• W. K. Lin, L. Ni, X. Wang, and J. L. Guo, and G. Xu, “Fabrication of a translational photoacoustic needle sensing probe for interstitial photoacoustic spectral analysis,” Photoacoustics 31:100519 (2023).
• L. Ni, X. Wang, and G. Xu, “Photoacoustic clinical applications: Musculoskeletal and abdominal imaging,” Z Med. Phys. 33(3): 324-335 (2023).
• Z. Xu, C. S. Locke, R. Morris, D. Jamison, K. M. Kozloff, and X. Wang, “Development of a semi-anthropomorphic photoacoustic calcaneus phantom based on nano computed tomography and stereolithography 3D printing,” J. Orthop. Res. doi: 10.1002/jor.25702. (2023).
• J. Folz, J. H. Wasserman, J. Jo, X. Wang, and R. Kopelman, “Photoacoustic Chemical Imaging Sodium Nano-Sensor Utilizing a Solvatochromic Dye Transducer for In Vivo Application,” Biosensors 13(10): 923 (2023).
• M. Wang, R. Singh, W. Zhang, J. S. Orringer, Y. M. Paulus, X. Yang, and X. Wang, “Cutaneous Hypervascularization Treatment Using Photo-Mediated Ultrasound Therapy,” JID Innov. 3(6):100237 (2023).
• Z. Xu, W. Zhang, C. Quesada, X. Wang, and M. Fabiilli, “Longitudinal monitoring of angiogenesis in a murine window chamber model in vivo,” Tissue Eng. Part C Methods doi:10.1089/ten.TEC.2023.0289 (2023).
• K. W. Chang, M. S. Karthikesh, Y. Zhu, H. M. Hudson, S. Barbay, D. Bundy, D. J. Guggenmos, S. Frost, R. J. Nudo, X. Wang, and X. Yang, “Photoacoustic imaging of squirrel monkey cortical responses induced by peripheral mechanical stimulation,” J. Biophotonics doi: 10.1002/jbio.202300347 (2024).
• Xueding Wang Complete Publications List

• 2005 Sontag Foundation Fellow of the Arthritis National Research Foundation
• 2005 Fairway-LaserSonix Young Investigator Award, SPIE Photonics West
• 2013 Distinguished Investigator Award, the Academy of Radiology Research
• 2020: Fellow, American Institute for Medical and Biological Engineering (AIMBE)
• 2022: Fellow, SPIE