News

Debating Bioethics

November 4, 2019

Bioengineers tend talk a lot about how new technologies work. BME Lecturer Barry Belmont also wants to discuss their implications, and he isn’t the only one.  “It’s one thing to learn the mechanics of gene therapy, for example, like how CRISPR works; it’s another to talk about some of the potential uses and the ethics […]

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Implantable cancer traps could provide earlier diagnosis and help monitor treatment Synthetic scaffolding could detect multiple types of cancers before they start to spread.| Medium Read

October 30, 2019

Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny “decoy” implanted just beneath the skin, University of Michigan researchers have demonstrated in mice. These devices have a knack for attracting cancer cells traveling through the body. In fact, they can even pick up signs that cancer […]

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Jon Rowley Receives BME Merit Award 2019 Michigan Biomedical Engineering Merit Award Recipient

October 23, 2019

Jon A. Rowley, a University of Michigan Undergraduate, Graduate, and Doctoral alumnus, was honored with the 2019 Michigan Biomedical Engineering Merit Award. Rowley is the Founder and Chief Product Officer of RoosterBio Inc. Jon started RoosterBio in 2013 as part of his personal quest of having the biggest impact possible on the commercial translation of […]

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Kelley Elahi Honored with BME Alumni Award 2019 Michigan Engineering Outstanding Recent Alumni Award Recipient

October 23, 2019

Kelley Elahi, a University of Michigan Biomedical Engineering alumnus, received this year’s Michigan Engineering Outstanding Recent Alumni Award. In only 8 years, Kelley has already established herself as an accomplished leader in global health. As a design engineer at MTTS in Hanoi, Vietnam, Kelley developed an infant continuous positive air pressure (CPAP) device to help […]

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Inspiration and innovation by design: New BME Design Spaces take shape

October 18, 2019

The University of Michigan Biomedical Engineering department will receive new state-of-the-art design, innovation and prototyping spaces through a complete renovation of the first floor of the Lurie Biomedical Engineering (LBME) Building. The 12,000-square-feet, $4.9 million renovation was approved Thursday by the Board of Regents. It will reinvent and redesign the space to create future-focused collaborative […]

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Shoe-box size breath-analyzer spots deadly lung disease faster, more accurately than doctors The device could also be used to detect other diseases such as pneumonia, sepsis, asthma and others associated with lung or systemic blood inflammation.

August 1, 2019

A small, portable breath monitor developed at the University of Michigan can quickly and accurately detect acute respiratory distress syndrome (ARDS), an often deadly disease that causes fluid to leak into the lungs and demands early diagnosis. To detect the condition today, doctors rely heavily on their own judgement, and time-consuming tests. The researchers say […]

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Injectable ‘bone spackling’: A cell therapy approach to heal complex fractures A Q&A with biomedical engineering professor Jan Stegemann, whose work in mice shows the promise of ‘microtissues.’

August 1, 2019

Large, complex bone wounds are hard for doctors and patients alike to contend with. They often require grafts and multiple surgeries. Jan Stegemann, a University of Michigan professor of biomedical engineering, is reprogramming adult cells from bone marrow so that they can be injected directly into a wound and grow into bone. The marrow-derived cells […]

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Overuse, or one bad move? New view on ACL tears prompt questions on how athletes train New research suggests a reevaluation of the way athletes train and prepare for competition.

July 29, 2019

Tears of the knee’s anterior cruciate ligament (ACL), a serious injury for athletes, may not just be the result of one instant of giving the joint more than it can handle, but rather the cumulative effect of less-severe, repeated stresses. It’s a finding from University of Michigan researchers that could have implications for athletes of […]

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An EpiPen for spinal cord injuries U-M researchers have designed nanoparticles that intercept immune cells on their way to the spinal cord and redirect them away from the injury.

July 9, 2019

An injection of nanoparticles can prevent the body’s immune system from overreacting to trauma, potentially preventing some spinal cord injuries from resulting in paralysis. The approach was demonstrated in mice at the University of Michigan, with the nanoparticles enhancing healing by reprogramming the aggressive immune cells. Call it an EpiPen for trauma to the central […]

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By Cannibalizing Nearby Stromal Stem Cells, Some Breast Cancer Cells Gain Invasion Advantage Cancer biologists and engineers collaborated on a device that could help predict the likelihood of breast cancer metastasis.

July 8, 2019

Researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have found that breast cancer cells that swallow up nearby stem cells take on some of their properties, enhancing their ability to invade other tissues throughout the body and seed secondary tumors, a process known as metastasis. It started with an unexpected observation […]

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Making connections: Designing a new neural interface module

July 5, 2019

About 300,000 individuals in the United States alone are living with a spinal cord injury, based on data gathered by the National Spinal Cord Injury Statistical Center, with nearly 18,000 new cases occurring each year. The injuries can be devastating, having a major impact on daily life, including on bowel and bladder control, the ability […]

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Kirigami can spin terahertz rays in real time to peer into biological tissue The rays used by airport scanners might have a future in medical imaging.

July 1, 2019

With a light-spinning device inspired by the Japanese art of paper cutting, University of Michigan researchers have detected microscopic twists in the internal structure of plant and animal tissue without harmful X-rays. The approach is the first that can fully rotate terahertz radiation in real time, and it could open new dimensions in medical imaging, […]

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Histotripsy: A potential approach to stroke treatment

June 28, 2019

Intracerebral hemorrhage, a life-altering type of hemorrhagic stroke, occurs in about 10 to 15 percent of all stroke cases. Individuals who suffer an ICH have a higher rate of disability and death – with about 60 percent of patients surviving at one month – than in other forms of stroke. Once the bleeding stops following […]

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Cancer is smarter than you think: Q&A with Geeta Mehta Decoding the sophisticated inner workings of cancer may help us fight it.

June 26, 2019

Geeta Mehta recently published a paper detailing integrated cancer tissue engineering models, which study cancer not simply as masses of cells but as structured organs with multiple cell types that communicate with each other and interact with the body—much like your lungs or liver. Mehta is the Dow Corning Assistant Professor of Materials Science and […]

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Making the invisible visible: New method opens unexplored realms for liquid biopsies A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma that might serve as disease- and organ-specific biomarkers

May 3, 2019

Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients’ blood and urine. These “liquid biopsies” are less invasive than a traditional biopsy, and can provide information about what’s happening throughout the body instead of just at a single site.

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Crackling and wheezing are more than just a sign of sickness Re-thinking what stethoscopes tell us.

April 17, 2019

Doctors know they’re the sounds of a problem in the lungs, but it turns out they might be more than symptoms—crackling and wheezing could also be the sounds of a disease progressing, according to a University of Michigan researcher.

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Taking shape: New aligned hydrogel tubes guide spinal tissue regeneration New aligned hydrogel tubes guide spinal tissue regeneration

April 8, 2019

Tissue engineering and regenerative medicine hold the promise of new treatment approaches to spinal cord injuries. Since the human body doesn’t naturally regenerate tissues of the spinal cord, new materials and structures that have similar characteristics to native tissue are needed to realize the potential.

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Recovering reproduction: U-M researchers stimulate follicle growth in mice aimed at creating eggs New approach can boost ovarian follicle survival in mice by up to 75 percent.

April 3, 2019

Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers.

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Speedy “slingshot” cell movement observed for the first time New findings suggest it might one day be possible to direct healthy cells to advance tissue repair therapies.

March 12, 2019

By slingshotting themselves forward, human cells can travel more than five times faster than previously documented, University of Michigan researchers have found.

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A ‘decathlon’ for antibiotics puts them through more realistic testing Surprise findings could upend the current drug discovery approach for treating one of the most dangerous hospital-borne infections.

January 23, 2019

The University of Michigan’s Sriram Chandrasekaran is using advanced computer simulations to study how different environments affect antibiotic performance.

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U-M BME and Shantou University Shaping the biomedical engineering workforce of tomorrow

December 13, 2018

A new international collaboration is underway, forging deeper connections between U-M BME and Shantou University (STU) in China. The two institutions are working side by side to develop a BME program at STU that will shape the biomedical engineering workforce of tomorrow.

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Has the Olympics changed how it measures false-starts in track? A Q&A with a biomechanics expert who has researched reaction times

August 30, 2018

In 2011, James Ashton-Miller, a Michigan Engineer, helped reveal that Olympic starting-line technology created a different experience for male and female sprinters. It did not accurately detect false starts by women. His latest work provides insights into what may, or may not, have happened since.

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Fifty years of Biomedical Engineering and Collaboration New Perspectives on What's Possible

July 3, 2018

The Biomedical Engineering department formally became a joint department of the U-M College of Engineering and the Medical School in 2012, just five years before celebrating its 50th anniversary in 2017. But the spirit and impact of the collaboration that spurred its founding five decades ago continue at an ever-increasing pace today. At the heart […]

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Toward a stem cell model of human nervous system development Human cells could one day show us more about why neural tube birth defects occur and how to prevent them.

June 15, 2018

Human embryonic stem cells can be guided to become the precursor tissue of the central nervous system, research led by the University of Michigan has demonstrated. The new study also reveals the important role of mechanical signals in the development of the human nervous system.

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BME-in-Practice: Iterative curriculum design

June 7, 2018

Incubators are common among entrepreneurs to nurture and develop a new product, application, or business idea. Assistant Professor Aileen Huang-Saad is also applying the concept to biomedical engineering practice – and to engineering education – through a novel “instructional incubator” and series of short, experiential courses.

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‘Nightmare bacteria:’ Michigan Engineers discuss how to combat antibiotic resistance Drug-resistant bugs are on the rise and new approaches are needed.

April 20, 2018

Health officials at the U.S. Centers for Disease Control and Prevention earlier this month said they are seeing rising cases of “nightmare bacteria” that show strong resistance to antibiotics. More than 200 cases were reported in the last year alone, and across every state in the U.S. “Unusual resistance germs—which are resistant to all or […]

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No sponge left behind: tags for surgical equipment A simple, easy-to-implement technology could prevent the debilitating injuries that can occur when organs are damaged by surgical tools left in the body.

April 15, 2018

Items left behind in patients after surgery can have an enormous personal cost when organs and tissues are damaged. Surgical sponges are among the worst offenders – difficult to see in post-surgical X-rays and yet capable of causing holes when the intestines grow around them, for example. These rare cases, estimated around one in 3,000 […]

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Carlos Aguilar wins highly competitive 2018 3M Non-tenured Faculty Award

April 6, 2018

Assistant Professor Carlos Aguilar has been selected to receive the 2018 3M Non-Tenured Faculty Award from the 3M Corporation. The 3M award recognizes outstanding faculty on the basis of research, experience, teaching and academic leadership. The award was created over twenty-five years ago by 3M’s Technical Community in partnership with the 3Mgives program to invest […]

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A Better Way to Connect Arteries How Coulter’s Newest Licensed Product Is Making Its Way from the Classroom to the Clinic

February 27, 2018

When reconstructive surgeons repair a breast after mastectomy or a severely injured leg after a car accident, they often move tissue harvested from one part of the body to another using microsurgical techniques. A new device developed at U-M and supported by the Coulter Translational Research Partnership Program will make it possible to connect arteries in the transferred tissue to those at the repair site in just minutes with a few easy steps.

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