News

Lab-on-a-chip offers faster means of identifying best plasma donors in COVID fight

October 1, 2020

University of Michigan collaboration with Hackensack Meridian CDI offers new pathway to identify antibodies. A new, portable lab-on-a-chip developed at the University of Michigan can identify the presence of COVID-19 antibodies in blood with greater speed and efficiency than the current standard “enzyme-linked immunosorbent assay” or ELISA technology. With assistance from U-M startup Optofluidic Bioassay and Hackensack Meridian […]

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New treatments for deadly lung disease could be revealed by 3D modeling

September 11, 2020

Traditional 2D research may rule out better treatment options. A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.  The causes of pulmonary fibrosis are not fully understood, but the condition is marked […]

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Brain interface pioneers find meaningful signal in the grey matter noise

July 28, 2020

by Dan Newman, Michigan Robotics Institute By tuning into a subset of brain waves, University of Michigan researchers have dramatically reduced the power requirements of neural interfaces while improving their accuracy. This discovery could lead to long-lasting brain implants that can both treat neurological diseases and enable mind-controlled prosthetics and machines. The team, led by Cynthia […]

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Improving Flexible Neural Probe Delivery Published in Nature: Microsystems & Nanoengineering

July 9, 2020

BME Prof. Tim Bruns, Affiliated Faculty members Euisik Yoon and John Seymour and their labs have developed a novel diamond shuttle to deliver a flexible neural probe that reduces surrounding tissue compression and blood vessel damage. The collaboration between faculty and students in Electrical Engineering and Computer Science and Biomedical Engineering included BME PhD student […]

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Study Suggests Method to Starve Pancreatic Cancer Cells

July 6, 2020

Rather than attacking cancer cells directly, new cell-model research probes weaknesses in pancreatic cancer’s interactions with other cells to obtain nutrients needed for tumor growth. A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature […]

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How rod-shaped particles might distract an out-of-control immune response

June 18, 2020

When white blood cells don’t know when to stop, an injection of rod-shaped particles may draw them away from a site of excessive inflammation. A long-ignored white blood cell may be central to the immune system overreaction that is the most common cause of death for COVID-19 patients—and University of Michigan researchers found that rod-shaped […]

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Supporting our Community: Black Lives Matter

June 5, 2020

U-M BME Chair Lonnie Shea shared the following message with the BME community on June 4, 2020, about standing up to racism and supporting the Black community. To All Members of the BME Community: Given the events of the past weeks, we wanted to reach out to our UM BME community.  Like most of you, […]

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Five BME Core Faculty and Five Affiliated/Associated Faculty Promoted

May 22, 2020

The University of Michigan Board of Regents approved a number of faculty promotions at their May meeting yesterday, including five core Biomedical Engineering faculty and five affiliated/associated Biomedical Engineering faculty. Core BME Faculty: Rhima M. Coleman, associate professor of biomedical engineering, with tenure, College of Engineering and Medical School; associate professor of mechanical engineering, without […]

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Improved neural probe can pose precise questions without losing parts of the answers

May 5, 2020

It will now be possible to study brain activity when timing is important, such as the consolidation of memory. A technique for studying individual circuits in the brains of mice has been hampered because the light needed to stimulate neural activity briefly overwhelms the electrodes “listening” for the response. Now, improved shielding within the neural […]

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Congratulations U-M Biomedical Engineering Graduates

April 30, 2020

U-M Biomedical Engineering would like to congratulate the BME ‘Class of 2020.’ We’re proud to celebrate the accomplishment of all of our graduates. This year we had 100 outstanding Bachelor’s degree graduates, 85 Master’s and SUGS graduates, and 24 Ph.D.s awarded.

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Lab-on-a-chip COVID-19 antibody test could offer rapid, accurate results

April 21, 2020

‘Anyone working on COVID-19 antibody tests can use their reagents in our device’| Medium Read Our campus, like the global community, is contending with COVID-19 and working to adapt to a new normal. Many are rapidly working on solutions. See all COVID-19 developments from University of Michigan Engineering. COVID-19 antibody testing that’s portable, fast, cheap and highly precise—four […]

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Charles Cain, PhD In Memoriam

March 29, 2020

Professor Charles Cain passed away on March 27, 2020, at the age of 77, after three years of fight with prostate cancer. Charles was born to be a scientist and educator. He only wanted to work on new concepts and despised being a follower. His creativity and desire to lead resulted in his pioneering phased […]

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Prof. Zhen Xu Receives Lockhart Memorial Prize from Focused Ultrasound Foundation

March 28, 2020

On March 25, Zhen Xu, PhD, associate professor in the Department of Biomedical Engineering at the University of Michigan, was awarded the 2019 Andrew J. Lockhart Memorial Prize by the Focused Ultrasound Foundation. The $75,000 annual prize is awarded to an investigator to recognize outstanding contributions in advancing cancer treatment using focused ultrasound and the potential for […]

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Covid-19: A guide for the BME Community

March 19, 2020

University of Michigan health professionals have been closely monitoring the spread of COVID-19 over the past two months. Our goals are to deliver on our mission while protecting health and safety by minimizing the potential spread of the disease, both within our community and in the broader society. The changes we have implemented follow the […]

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‘It’s like you have a hand again’ An ultra-precise mind-controlled prosthetic

March 4, 2020

In a major advance in mind-controlled prosthetics for amputees, University of Michigan researchers have tapped faint, latent signals from arm nerves and amplified them to enable real-time, intuitive, finger-level control of a robotic hand. Take an interactive multimedia deep dive into the research collaboration that’s powering the unprecedented, intuitive control of next-gen bionics. Read the […]

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Aaron Morris Selected as a TED Fellow University of Michigan Precision Health Scholar and Biomedical Engineering Postdoc to present at TED2020

January 23, 2020

Ann Arbor, MI JANUARY 23, 2020—Aaron Morris, MS, PhD—a 2018 recipient of a Precision Health Scholars Award and a research fellow in Biomedical Engineering at the University of Michigan—has been selected as a TED Fellow. Chosen for his work on tissue-engineered diagnostic sites, Morris joins a class of 20 change-makers from around the world to […]

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How an AI solution can design new tuberculosis drug regimens A new method could replace trial and error drug development

November 21, 2019

With a shortage of new tuberculosis drugs in the pipeline, a software tool from the University of Michigan can predict how current drugs—including unlikely candidates—can be combined in new ways to create more effective treatments. “This could replace our traditional trial-and-error system for drug development that is comparatively slow and expensive,” said Sriram Chandrasekaran, a U-M […]

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Debating Bioethics

November 4, 2019

Bioengineers tend talk a lot about how new technologies work. BME Lecturer Barry Belmont also wants to discuss their implications, and he isn’t the only one.  “It’s one thing to learn the mechanics of gene therapy, for example, like how CRISPR works; it’s another to talk about some of the potential uses and the ethics […]

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Implantable cancer traps could provide earlier diagnosis and help monitor treatment Synthetic scaffolding could detect multiple types of cancers before they start to spread.| Medium Read

October 30, 2019

Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny “decoy” implanted just beneath the skin, University of Michigan researchers have demonstrated in mice. These devices have a knack for attracting cancer cells traveling through the body. In fact, they can even pick up signs that cancer […]

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Jon Rowley Receives BME Merit Award 2019 Michigan Biomedical Engineering Merit Award Recipient

October 23, 2019

Jon A. Rowley, a University of Michigan Undergraduate, Graduate, and Doctoral alumnus, was honored with the 2019 Michigan Biomedical Engineering Merit Award. Rowley is the Founder and Chief Product Officer of RoosterBio Inc. Jon started RoosterBio in 2013 as part of his personal quest of having the biggest impact possible on the commercial translation of […]

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Kelley Elahi Honored with BME Alumni Award 2019 Michigan Engineering Outstanding Recent Alumni Award Recipient

October 23, 2019

Kelley Elahi, a University of Michigan Biomedical Engineering alumnus, received this year’s Michigan Engineering Outstanding Recent Alumni Award. In only 8 years, Kelley has already established herself as an accomplished leader in global health. As a design engineer at MTTS in Hanoi, Vietnam, Kelley developed an infant continuous positive air pressure (CPAP) device to help […]

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Inspiration and innovation by design: New BME Design Spaces take shape

October 18, 2019

The University of Michigan Biomedical Engineering department will receive new state-of-the-art design, innovation and prototyping spaces through a complete renovation of the first floor of the Lurie Biomedical Engineering (LBME) Building. The 12,000-square-feet, $4.9 million renovation was approved Thursday by the Board of Regents. It will reinvent and redesign the space to create future-focused collaborative […]

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Shoe-box size breath-analyzer spots deadly lung disease faster, more accurately than doctors The device could also be used to detect other diseases such as pneumonia, sepsis, asthma and others associated with lung or systemic blood inflammation.

August 1, 2019

A small, portable breath monitor developed at the University of Michigan can quickly and accurately detect acute respiratory distress syndrome (ARDS), an often deadly disease that causes fluid to leak into the lungs and demands early diagnosis. To detect the condition today, doctors rely heavily on their own judgement, and time-consuming tests. The researchers say […]

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Injectable ‘bone spackling’: A cell therapy approach to heal complex fractures A Q&A with biomedical engineering professor Jan Stegemann, whose work in mice shows the promise of ‘microtissues.’

August 1, 2019

Large, complex bone wounds are hard for doctors and patients alike to contend with. They often require grafts and multiple surgeries. Jan Stegemann, a University of Michigan professor of biomedical engineering, is reprogramming adult cells from bone marrow so that they can be injected directly into a wound and grow into bone. The marrow-derived cells […]

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Overuse, or one bad move? New view on ACL tears prompt questions on how athletes train New research suggests a reevaluation of the way athletes train and prepare for competition.

July 29, 2019

Tears of the knee’s anterior cruciate ligament (ACL), a serious injury for athletes, may not just be the result of one instant of giving the joint more than it can handle, but rather the cumulative effect of less-severe, repeated stresses. It’s a finding from University of Michigan researchers that could have implications for athletes of […]

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An EpiPen for spinal cord injuries U-M researchers have designed nanoparticles that intercept immune cells on their way to the spinal cord and redirect them away from the injury.

July 9, 2019

An injection of nanoparticles can prevent the body’s immune system from overreacting to trauma, potentially preventing some spinal cord injuries from resulting in paralysis. The approach was demonstrated in mice at the University of Michigan, with the nanoparticles enhancing healing by reprogramming the aggressive immune cells. Call it an EpiPen for trauma to the central […]

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By Cannibalizing Nearby Stromal Stem Cells, Some Breast Cancer Cells Gain Invasion Advantage Cancer biologists and engineers collaborated on a device that could help predict the likelihood of breast cancer metastasis.

July 8, 2019

Researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have found that breast cancer cells that swallow up nearby stem cells take on some of their properties, enhancing their ability to invade other tissues throughout the body and seed secondary tumors, a process known as metastasis. It started with an unexpected observation […]

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Making connections: Designing a new neural interface module

July 5, 2019

About 300,000 individuals in the United States alone are living with a spinal cord injury, based on data gathered by the National Spinal Cord Injury Statistical Center, with nearly 18,000 new cases occurring each year. The injuries can be devastating, having a major impact on daily life, including on bowel and bladder control, the ability […]

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Kirigami can spin terahertz rays in real time to peer into biological tissue The rays used by airport scanners might have a future in medical imaging.

July 1, 2019

With a light-spinning device inspired by the Japanese art of paper cutting, University of Michigan researchers have detected microscopic twists in the internal structure of plant and animal tissue without harmful X-rays. The approach is the first that can fully rotate terahertz radiation in real time, and it could open new dimensions in medical imaging, […]

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Histotripsy: A potential approach to stroke treatment

June 28, 2019

Intracerebral hemorrhage, a life-altering type of hemorrhagic stroke, occurs in about 10 to 15 percent of all stroke cases. Individuals who suffer an ICH have a higher rate of disability and death – with about 60 percent of patients surviving at one month – than in other forms of stroke. Once the bleeding stops following […]

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Cancer is smarter than you think: Q&A with Geeta Mehta Decoding the sophisticated inner workings of cancer may help us fight it.

June 26, 2019

Geeta Mehta recently published a paper detailing integrated cancer tissue engineering models, which study cancer not simply as masses of cells but as structured organs with multiple cell types that communicate with each other and interact with the body—much like your lungs or liver. Mehta is the Dow Corning Assistant Professor of Materials Science and […]

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Making the invisible visible: New method opens unexplored realms for liquid biopsies A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma that might serve as disease- and organ-specific biomarkers

May 3, 2019

Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients’ blood and urine. These “liquid biopsies” are less invasive than a traditional biopsy, and can provide information about what’s happening throughout the body instead of just at a single site.

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Crackling and wheezing are more than just a sign of sickness Re-thinking what stethoscopes tell us.

April 17, 2019

Doctors know they’re the sounds of a problem in the lungs, but it turns out they might be more than symptoms—crackling and wheezing could also be the sounds of a disease progressing, according to a University of Michigan researcher.

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Taking shape: New aligned hydrogel tubes guide spinal tissue regeneration New aligned hydrogel tubes guide spinal tissue regeneration

April 8, 2019

Tissue engineering and regenerative medicine hold the promise of new treatment approaches to spinal cord injuries. Since the human body doesn’t naturally regenerate tissues of the spinal cord, new materials and structures that have similar characteristics to native tissue are needed to realize the potential.

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Recovering reproduction: U-M researchers stimulate follicle growth in mice aimed at creating eggs New approach can boost ovarian follicle survival in mice by up to 75 percent.

April 3, 2019

Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers.

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Speedy “slingshot” cell movement observed for the first time New findings suggest it might one day be possible to direct healthy cells to advance tissue repair therapies.

March 12, 2019

By slingshotting themselves forward, human cells can travel more than five times faster than previously documented, University of Michigan researchers have found.

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A ‘decathlon’ for antibiotics puts them through more realistic testing Surprise findings could upend the current drug discovery approach for treating one of the most dangerous hospital-borne infections.

January 23, 2019

The University of Michigan’s Sriram Chandrasekaran is using advanced computer simulations to study how different environments affect antibiotic performance.

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U-M BME and Shantou University Shaping the biomedical engineering workforce of tomorrow

December 13, 2018

A new international collaboration is underway, forging deeper connections between U-M BME and Shantou University (STU) in China. The two institutions are working side by side to develop a BME program at STU that will shape the biomedical engineering workforce of tomorrow.

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Has the Olympics changed how it measures false-starts in track? A Q&A with a biomechanics expert who has researched reaction times

August 30, 2018

In 2011, James Ashton-Miller, a Michigan Engineer, helped reveal that Olympic starting-line technology created a different experience for male and female sprinters. It did not accurately detect false starts by women. His latest work provides insights into what may, or may not, have happened since.

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Fifty years of Biomedical Engineering and Collaboration New Perspectives on What's Possible

July 3, 2018

The Biomedical Engineering department formally became a joint department of the U-M College of Engineering and the Medical School in 2012, just five years before celebrating its 50th anniversary in 2017. But the spirit and impact of the collaboration that spurred its founding five decades ago continue at an ever-increasing pace today. At the heart […]

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