News

Ultrasound Technology Developed at U-M Now in Clinical Trials for Liver Cancer

June 7, 2021

The University of Michigan is one of eight sites around the country that will enroll patients in a clinical trial to evaluate the safety and efficacy of a technology that uses ultrasound to treat liver tumors.

The #HOPE4LIVER trial will employ the noninvasive technique to mechanically destroy primary and metastatic liver tumors.

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Incoming BME Assistant Professor Aaron Morris’ ‘TED Talk’ released

May 24, 2021

Aaron Morris, Ph.D., an incoming BME assistant professor and current research fellow in the Shea Lab, was selected as a 2020 TED fellow and will participate in a first-ever fellows takeover of TED.com starting on Monday, May 24, 2021. Morris’ talk, titled “The future diagnostic lab inside your body“, will be published on TED.com and […]

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Immunotherapy: The Next Generation

March 8, 2021

BME recently hosted a virtual seminar for alumni and friends on February 23rd, 2021, presented by Professor Lonnie Shea, William and Valerie Hall Chair of Biomedical Engineering, and Dr. Jacqueline Jeruss, Associate Dean for Regulatory Affairs and professor on “Immunotherapy: The Next Generation.” The event was hosted by William Hall, Michigan Engineering Alumnus and Supporter, […]

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Ideation and Collaboration

March 8, 2021

New BME spaces with educational and design focus poised to reshape Biomedical Engineering learning and teaching It was announced in the Fall of 2019 that the first floor of the LBME building would receive a new 12,000 square feet, $5 million dollar renovation that would reinvent and redesign the BME Design Spaces with a focus […]

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New Non-Contact Technique Allows for Quantitative Characterization of Soft Biomaterials

February 18, 2021

Conventional rheology methods face limitations that can now be bypassed through the application of Resonant Acoustic Rheometry (RAR,) a new ultrasound-based technique that is helpful in identifying properties of soft biomaterials, such as hydrogels. Hydrogels are commonly used as a model of the extracellular matrix and help to recapitulate the structure and function of a […]

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Method of Immunomodulation at Biomaterial Scaffolds Can Help Detect Early Pancreatic Cancer

February 16, 2021

Individuals with pancreatic cancer face a worse disease prognosis than those diagnosed with other forms of cancer, as stage IV pancreatic cancer has a five year survival rate of 1 percent. The survival rate of localized pancreatic cancer is around 33%, while many other cancers have a rate exceeding 90%. This is largely a result […]

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Open BME Seminar Series

February 1, 2021

We are thrilled to announce that The University of Michigan will be a part of the Open BME Seminar Series this Winter and Spring. This virtual series is being coordinated by seven of the leading BME departments across the country. The goal is to expose our graduate students to cutting edge ideas in the field of biomedical […]

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How to end discrimination in health research funding

January 27, 2021

by Kate McAlpine | Michigan Engineering Network of U.S. biomedical engineering researchers calls to end funding disparities between Black and white scientists. White researchers are nearly twice as likely to be awarded a grant than Black scientists of similar academic achievement, studies of National Institutes of Health funding programs show—and a group of 19 biomedical engineering […]

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Research Team Awarded $2M NIH Grant for Breath Analyzer that Detects and Monitors COVID-19, COVID-19 Induced Lung Injury

January 26, 2021

Across the United States, there has been a marked increase in COVID-19 cases as many states tentatively reopen. This has resulted in a critical need for screening, diagnosing, and monitoring technologies that can process results quickly and can be used in both clinical and everyday settings.  In December of 2020, a research team led by […]

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Treating autoimmune disorders with an inhaler, rather than an IV

December 7, 2020

Research in mice shows efficacy for multiple sclerosis. Nanoparticles continue to find wider use in medical treatments in everything from drug delivery to diagnosing disease. In nearly every case, these ultrafine particles are delivered to patients via injection or through an IV. Biomedical engineers at the University of Michigan are exploring how nanoparticles that are […]

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Undergrads awarded by NASA, European Space Agency for project predicting COVID hotspots

November 11, 2020

The team earned the Best Use of Science award at the NASA Space Apps COVID-19 Challenge for their machine learning model that can predict hotspots for COVID outbreaks Five undergrad students majoring in computer science and biomedical engineering were recognized at a global 48-hour hackathon hosted by NASA to tackle the many challenges surrounding the […]

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Researchers Argue for a More Systematic Use of Mathematical Models To Study Neurotechnologies

November 10, 2020

Study calls into question rush to use brain stimulation technology to treat Parkinson’s and pain disorders. Electrical stimulation or neurostimulation technologies work for treating a wide range of neurological disorders, like chronic pain and Parkinson’s disease. In these technologies, electrical pulses are delivered from electrodes placed inside the brain or outside the skin to generate […]

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Lab-on-a-chip offers faster means of identifying best plasma donors in COVID fight

October 1, 2020

University of Michigan collaboration with Hackensack Meridian CDI offers new pathway to identify antibodies. A new, portable lab-on-a-chip used by University of Michigan researchers can identify the presence of COVID-19 antibodies in blood with greater speed and efficiency than the current standard “enzyme-linked immunosorbent assay” or ELISA technology. With assistance from U-M startup Optofluidic Bioassay and Hackensack Meridian […]

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New treatments for deadly lung disease could be revealed by 3D modeling

September 11, 2020

Traditional 2D research may rule out better treatment options. A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.  The causes of pulmonary fibrosis are not fully understood, but the condition is marked […]

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Brain interface pioneers find meaningful signal in the grey matter noise

July 28, 2020

by Dan Newman, Michigan Robotics Institute By tuning into a subset of brain waves, University of Michigan researchers have dramatically reduced the power requirements of neural interfaces while improving their accuracy. This discovery could lead to long-lasting brain implants that can both treat neurological diseases and enable mind-controlled prosthetics and machines. The team, led by Cynthia […]

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Improving Flexible Neural Probe Delivery Published in Nature: Microsystems & Nanoengineering

July 9, 2020

BME Prof. Tim Bruns, Affiliated Faculty members Euisik Yoon and John Seymour and their labs have developed a novel diamond shuttle to deliver a flexible neural probe that reduces surrounding tissue compression and blood vessel damage. The collaboration between faculty and students in Electrical Engineering and Computer Science and Biomedical Engineering included BME PhD student […]

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Study Suggests Method to Starve Pancreatic Cancer Cells

July 6, 2020

Rather than attacking cancer cells directly, new cell-model research probes weaknesses in pancreatic cancer’s interactions with other cells to obtain nutrients needed for tumor growth. A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature […]

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How rod-shaped particles might distract an out-of-control immune response

June 18, 2020

When white blood cells don’t know when to stop, an injection of rod-shaped particles may draw them away from a site of excessive inflammation. A long-ignored white blood cell may be central to the immune system overreaction that is the most common cause of death for COVID-19 patients—and University of Michigan researchers found that rod-shaped […]

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Supporting our Community: Black Lives Matter

June 5, 2020

U-M BME Chair Lonnie Shea shared the following message with the BME community on June 4, 2020, about standing up to racism and supporting the Black community. To All Members of the BME Community: Given the events of the past weeks, we wanted to reach out to our UM BME community.  Like most of you, […]

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Five BME Core Faculty and Five Affiliated/Associated Faculty Promoted

May 22, 2020

The University of Michigan Board of Regents approved a number of faculty promotions at their May meeting yesterday, including five core Biomedical Engineering faculty and five affiliated/associated Biomedical Engineering faculty. Core BME Faculty: Rhima M. Coleman, associate professor of biomedical engineering, with tenure, College of Engineering and Medical School; associate professor of mechanical engineering, without […]

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Improved neural probe can pose precise questions without losing parts of the answers

May 5, 2020

It will now be possible to study brain activity when timing is important, such as the consolidation of memory. A technique for studying individual circuits in the brains of mice has been hampered because the light needed to stimulate neural activity briefly overwhelms the electrodes “listening” for the response. Now, improved shielding within the neural […]

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Congratulations U-M Biomedical Engineering Graduates

April 30, 2020

U-M Biomedical Engineering would like to congratulate the BME ‘Class of 2020.’ We’re proud to celebrate the accomplishment of all of our graduates. This year we had 100 outstanding Bachelor’s degree graduates, 85 Master’s and SUGS graduates, and 24 Ph.D.s awarded.

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Lab-on-a-chip COVID-19 antibody test could offer rapid, accurate results

April 21, 2020

‘Anyone working on COVID-19 antibody tests can use their reagents in our device’| Medium Read Our campus, like the global community, is contending with COVID-19 and working to adapt to a new normal. Many are rapidly working on solutions. See all COVID-19 developments from University of Michigan Engineering. COVID-19 antibody testing that’s portable, fast, cheap and highly precise—four […]

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Charles Cain, PhD In Memoriam

March 29, 2020

Professor Charles Cain passed away on March 27, 2020, at the age of 77, after three years of fight with prostate cancer. Charles was born to be a scientist and educator. He only wanted to work on new concepts and despised being a follower. His creativity and desire to lead resulted in his pioneering phased […]

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Prof. Zhen Xu Receives Lockhart Memorial Prize from Focused Ultrasound Foundation

March 28, 2020

On March 25, Zhen Xu, PhD, associate professor in the Department of Biomedical Engineering at the University of Michigan, was awarded the 2019 Andrew J. Lockhart Memorial Prize by the Focused Ultrasound Foundation. The $75,000 annual prize is awarded to an investigator to recognize outstanding contributions in advancing cancer treatment using focused ultrasound and the potential for […]

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Covid-19: A guide for the BME Community

March 19, 2020

University of Michigan health professionals have been closely monitoring the spread of COVID-19 over the past two months. Our goals are to deliver on our mission while protecting health and safety by minimizing the potential spread of the disease, both within our community and in the broader society. The changes we have implemented follow the […]

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‘It’s like you have a hand again’ An ultra-precise mind-controlled prosthetic

March 4, 2020

In a major advance in mind-controlled prosthetics for amputees, University of Michigan researchers have tapped faint, latent signals from arm nerves and amplified them to enable real-time, intuitive, finger-level control of a robotic hand. Take an interactive multimedia deep dive into the research collaboration that’s powering the unprecedented, intuitive control of next-gen bionics. Read the […]

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Aaron Morris Selected as a TED Fellow University of Michigan Precision Health Scholar and Biomedical Engineering Postdoc to present at TED2020

January 23, 2020

Ann Arbor, MI JANUARY 23, 2020—Aaron Morris, MS, PhD—a 2018 recipient of a Precision Health Scholars Award and a research fellow in Biomedical Engineering at the University of Michigan—has been selected as a TED Fellow. Chosen for his work on tissue-engineered diagnostic sites, Morris joins a class of 20 change-makers from around the world to […]

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How an AI solution can design new tuberculosis drug regimens A new method could replace trial and error drug development

November 21, 2019

With a shortage of new tuberculosis drugs in the pipeline, a software tool from the University of Michigan can predict how current drugs—including unlikely candidates—can be combined in new ways to create more effective treatments. “This could replace our traditional trial-and-error system for drug development that is comparatively slow and expensive,” said Sriram Chandrasekaran, a U-M […]

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Debating Bioethics

November 4, 2019

Bioengineers tend talk a lot about how new technologies work. BME Lecturer Barry Belmont also wants to discuss their implications, and he isn’t the only one.  “It’s one thing to learn the mechanics of gene therapy, for example, like how CRISPR works; it’s another to talk about some of the potential uses and the ethics […]

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Implantable cancer traps could provide earlier diagnosis and help monitor treatment Synthetic scaffolding could detect multiple types of cancers before they start to spread.| Medium Read

October 30, 2019

Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny “decoy” implanted just beneath the skin, University of Michigan researchers have demonstrated in mice. These devices have a knack for attracting cancer cells traveling through the body. In fact, they can even pick up signs that cancer […]

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Jon Rowley Receives BME Merit Award 2019 Michigan Biomedical Engineering Merit Award Recipient

October 23, 2019

Jon A. Rowley, a University of Michigan Undergraduate, Graduate, and Doctoral alumnus, was honored with the 2019 Michigan Biomedical Engineering Merit Award. Rowley is the Founder and Chief Product Officer of RoosterBio Inc. Jon started RoosterBio in 2013 as part of his personal quest of having the biggest impact possible on the commercial translation of […]

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Kelley Elahi Honored with BME Alumni Award 2019 Michigan Engineering Outstanding Recent Alumni Award Recipient

October 23, 2019

Kelley Elahi, a University of Michigan Biomedical Engineering alumnus, received this year’s Michigan Engineering Outstanding Recent Alumni Award. In only 8 years, Kelley has already established herself as an accomplished leader in global health. As a design engineer at MTTS in Hanoi, Vietnam, Kelley developed an infant continuous positive air pressure (CPAP) device to help […]

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Inspiration and innovation by design: New BME Design Spaces take shape

October 18, 2019

The University of Michigan Biomedical Engineering department will receive new state-of-the-art design, innovation and prototyping spaces through a complete renovation of the first floor of the Lurie Biomedical Engineering (LBME) Building. The 12,000-square-feet, $4.9 million renovation was approved Thursday by the Board of Regents. It will reinvent and redesign the space to create future-focused collaborative […]

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Shoe-box size breath-analyzer spots deadly lung disease faster, more accurately than doctors The device could also be used to detect other diseases such as pneumonia, sepsis, asthma and others associated with lung or systemic blood inflammation.

August 1, 2019

A small, portable breath monitor developed at the University of Michigan can quickly and accurately detect acute respiratory distress syndrome (ARDS), an often deadly disease that causes fluid to leak into the lungs and demands early diagnosis. To detect the condition today, doctors rely heavily on their own judgement, and time-consuming tests. The researchers say […]

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Injectable ‘bone spackling’: A cell therapy approach to heal complex fractures A Q&A with biomedical engineering professor Jan Stegemann, whose work in mice shows the promise of ‘microtissues.’

August 1, 2019

Large, complex bone wounds are hard for doctors and patients alike to contend with. They often require grafts and multiple surgeries. Jan Stegemann, a University of Michigan professor of biomedical engineering, is reprogramming adult cells from bone marrow so that they can be injected directly into a wound and grow into bone. The marrow-derived cells […]

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Overuse, or one bad move? New view on ACL tears prompt questions on how athletes train New research suggests a reevaluation of the way athletes train and prepare for competition.

July 29, 2019

Tears of the knee’s anterior cruciate ligament (ACL), a serious injury for athletes, may not just be the result of one instant of giving the joint more than it can handle, but rather the cumulative effect of less-severe, repeated stresses. It’s a finding from University of Michigan researchers that could have implications for athletes of […]

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An EpiPen for spinal cord injuries U-M researchers have designed nanoparticles that intercept immune cells on their way to the spinal cord and redirect them away from the injury.

July 9, 2019

An injection of nanoparticles can prevent the body’s immune system from overreacting to trauma, potentially preventing some spinal cord injuries from resulting in paralysis. The approach was demonstrated in mice at the University of Michigan, with the nanoparticles enhancing healing by reprogramming the aggressive immune cells. Call it an EpiPen for trauma to the central […]

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By Cannibalizing Nearby Stromal Stem Cells, Some Breast Cancer Cells Gain Invasion Advantage Cancer biologists and engineers collaborated on a device that could help predict the likelihood of breast cancer metastasis.

July 8, 2019

Researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have found that breast cancer cells that swallow up nearby stem cells take on some of their properties, enhancing their ability to invade other tissues throughout the body and seed secondary tumors, a process known as metastasis. It started with an unexpected observation […]

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Making connections: Designing a new neural interface module

July 5, 2019

About 300,000 individuals in the United States alone are living with a spinal cord injury, based on data gathered by the National Spinal Cord Injury Statistical Center, with nearly 18,000 new cases occurring each year. The injuries can be devastating, having a major impact on daily life, including on bowel and bladder control, the ability […]

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