News

Closest look yet at killer T-cell activity could yield new approach to tackling antibiotic resistance An in-depth look at the work of T-cells, the body's bacteria killers, could provide a roadmap to effective drug treatments.

In a study that could provide a roadmap for combatting the rising threat of drug-resistant pathogens, researchers have discovered the specific mechanism the body’s T-Cells use to kill bacteria.

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Identifying New Targets in Cancer Metabolism and Treatment

Progress in cancer research over the past ten years has helped scientists gain a greater understanding of cancer cell metabolism and how cancer cells interact…

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Bionic heart tissue: U-Michigan part of $20M center Scar tissue left over from heart attacks creates dead zones that don’t beat. Bioengineered patches could fix that.

The University of Michigan is partnering on an ambitious $20 million project to grow new heart tissue for cardiac patients.

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Reading cancer’s chemical clues A nanoparticle-assisted optical imaging technique could one day read the chemical makeup of a tumor.

A tumor’s chemical makeup holds valuable clues about how to fight it. But today, it’s difficult or impossible to examine the chemistry inside a tumor.

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$7.75M for mapping circuits in the brain A new NSF Tech Hub will put tools to rapidly advance our understanding of the brain into the hands of neuroscientists.

The technology exists to stimulate and map circuits in the brain, but neuroscientists have yet to tap this potential.

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Lab-grown lung tissue could lead to new cancer, asthma treatments A look at how Michigan Engineers created a biomaterial scaffold to help researchers from the U-M Medical School grow mature human lung tissue.

In a breakthrough that could one day lead to new treatments for lung diseases like asthma and lung cancer, researchers have successfully coaxed stem cells—the body’s master cells—to grow into three-dimensional lung tissue.

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Mildred F. Denecke Scholarship Fund endowed The fund will provide need-based support for students in the Department of Biomedical Engineering (BME).

Mildred F. Denecke (BSE Phys ’49) recently made a gift to endow the Mildred F. Denecke Scholarship Fund. The fund will provide need-based support for students in the Department of Biomedical Engineering (BME).

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Bright ideas Master's student research explores concept generation in design

Generating ideas during an engineering design process is crucial to developing successful solutions. But teaching – and learning – about idea generation in design is challenging for instructors and students alike.

Anastasia Ostrowski (BSE BME ’16, MSE BME ’17), has been conducting research with the aim of providing insights to improve idea generation, and therefore design education, for BME students.

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M-HEAL + Mentors = Design Progress

The student-run organization M-HEAL, Michigan Health Engineered for All Lives, has a laudable, and ambitious, mission: to design healthcare solutions in collaboration with international partners to positively impact global health.

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Improving medical devices Collaboration by design

A new experiential learning opportunity at U-M, the Medical Device Sandbox (MDS), helps both BME students and health care learners, including medical students, residents, nurses, and other health providers, collaborate across disciplines to improve device design and, ultimately, patient safety

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Understanding pediatric pulmonary hypertension Creating new imaging and modeling tools to improve diagnosis and management

Pulmonary hypertension (PH), a lung disorder that causes high blood pressure in the pulmonary arteries, affects an estimated 15 million to 50 million individuals worldwide. Its progressive nature, impact on quality of life, and life-threatening long-term consequences make it an important focus of basic scientific and translational research.

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Undergrad Caroline Woody named a contributing author of Science article Advancing the understanding of HIV treatment

It’s not every day that a first-year undergraduate is named a contributing author on a research article, particularly high-impact work published in the prestigious journal Science. Caroline Woody, now a sophomore, has earned that distinction.

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‘Sister cell’ profiling aims to shut down cancer metastasis Michigan engineers release individual cells from a specially-designed chip using laser pulses.

In work that could improve understanding of how cancer spreads, a team of engineers and medical researchers at the University of Michigan developed a new kind of microfluidic chip that can capture rare, aggressive cancer cells, grow them on the chip and release single cells on demand.

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Keeping drugs on the job

Computer simulations developed at the University of Michigan reveal how well drug additives stop the active ingredients from crystallizing in the digestive tract. They tested these simulations on the anti-seizure drug phenytoin.

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Collaboration between Project MESA and Washtenaw Community College’s Advanced Fabrication Program

M-HEAL’s Project MESA has been finalizing its design of a portable gynecological examination table for use in rural mobile clinics in Nicaragua. In addition to improving the design’s comfort, durability, and clinical features, they have been working to simplify manufacturing of their product. The group connected with Amanda Scheffler, a welding instructor at Washtenaw Community College (WCC).

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Four BME students receive NSF Graduate Research Fellowships

U-M Biomedical Engineering had four National Science Foundation (NSF) Graduate Research Fellowship award winners in 2017.

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U-M Schools and Colleges Form Regenerative Medicine Collaborative

ANN ARBOR, MI –A Regenerative Medicine Collaborative, formed with support from U-M Office of Research, College of Engineering, and School of Medicine, aims to foster connections and enable new initiatives among investigators at the major U-M schools and colleges, including: U-M Engineering, Medical School, Dentistry, LSA, Public Health, and Pharmacy.

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U-M leads major new regenerative medicine center funded by NIH

ANN ARBOR—A new interdisciplinary health sciences resource center at the University of Michigan has received an $11.7 million award from the National Institutes of Health to advance regenerative medicine.

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Coating method could improve temporary implants that dissolve in the body

A strategy for coating complicated surfaces with biodegradable polymers has been pioneered by a team of researchers led by Joerg Lahann, a professor of chemical engineering and director of the Biointerfaces Institute at U-M. It could enable coatings for implants that dissolve in the body, such as drugs to improve healing.

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Tim Bruns wins NSF CAREER Award

U-M BME assistant professor Tim Bruns has received a prestigious National Science Foundation Faculty Early Career Development (CAREER) Award.

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3-D printed orthotics and prosthetics: A better fit, the same day

A new way to design and 3D print custom prosthetics and orthotics could give amputees, stroke patients and individuals with cerebral palsy lighter, better-fitting assistive devices in a fraction of the time it takes to get them today.

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Ellen Arruda elected as a member of the National Academy of Engineering

Mechanical Engineering, Biomedical Engineering and Macromolecular Science and Engineering, Professor Ellen Arruda, has been elected as a member of the National Academy of Engineering (NAE).

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‘5-D protein fingerprinting’ could give insights into Alzheimer’s, Parkinson’s

ANN ARBOR—In research that could one day lead to advances against neurodegenerative diseases like Alzheimer’s and Parkinson’s, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid. Proteins are essential to the function of every cell. Measuring their properties in blood and other […]

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Meet the new BME faculty

On January 2, 2017, five new faculty started at U-M Biomedical Engineering. Each brings their own expertise in diverse areas, adding to U-M BME’s many strengths. Carlos Andres Aguilar Assistant Professor Integrative Genomics Carlos Andres Aguilar joins BME in January. He will use his background in muscle stem cell biology, epigenetic regulation, and micro/nanofabricated devices […]

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U-M, colleges team up in biomedical science teaching and learning

They’re at two different ends of the higher-education journey: some just starting out on associate’s degrees, others finishing up advanced training after earning a doctorate in biomedical science.

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BME PhD student Yiying Zhu wins 2016 ESB EDGE Award

U-M Biomedical Engineering PhD student Yiying Zhu, out of Dr. Oliver Kripfgans Ultrasound Group in Radiology, was selected as one of the recipients of the 2016 Endowment for the Development of Graduate Education (EDGE) award.

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U-M research center spurs new approach to musculoskeletal health

ANN ARBOR – A promising new approach to musculoskeletal disease that focuses on the interactions between body systems like bone and muscle is a top priority at the newly established Michigan Integrative Musculoskeletal Health Core Center.

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M-HEAL’S Project MESA Wins $25K from Ford C3 Prize supports distribution of team’s portable exam table in Nicaragua

A team of U-M students is one of seven across the country to win $25,000 in the 2016 Ford College Community Challenge (Ford C3).

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Clinical Peer Mentors Identifying clinical needs and resources for the BME design program

This summer marks the second round of a new clinical peer mentor (CPM) program that offers internships to BME students interested in documenting clinical needs and resources for BME design courses.

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Turning blood into a laser emitter for drug testing, cancer treatment

University of Michigan researchers have successfully demonstrated a new technique that combines laser light with an FDA-approved fluorescent dye to monitor cell structure and activity at the molecular level.

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