BME Project 8: Overcoming immune responses

Faculty mentor: Lonnie Shea, Ph.D.
Required skills: Interest in in vitro and in vivo research. Attention to detail. Curiosity and independent decision-making skills desired.
We are using biocompatible nanoparticles to delivery peptides in a way that reverses immune disorders. However, there is the potential for undesired immunological responses that can occur in individuals with a history of specific peptide exposure. We are investigating nanoparticle cell interactions and immune recognition of particles. This project will involve nanoparticle fabrication, cell culture, and assessment of immune responses in mouse models.