Dr. Xu’s research focuses on developing new ultrasound technique for treatment of cancer, cardiovascular diseases, and neurological diseases. She and her colleagues have developed histotripsy, an ultrasound ablation technique via controlled cavitation. Histotripsy is the first image-guided ablation technique that is non-invasive, non-ionizing, and non-thermal. Dr. Xu’s work spans from basic science, device development, preclinical investigations, to clinical translation of histotripsy.