Understanding pediatric pulmonary hypertension Creating new imaging and modeling tools to improve diagnosis and management

Pulmonary hypertension (PH), a lung disorder that causes high blood pressure in the pulmonary arteries, affects an estimated 15 million to 50 million individuals worldwide. Its progressive nature, impact on quality of life, and life-threatening long-term consequences make it an important focus of basic scientific and translational research.

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Keeping drugs on the job

Computer simulations developed at the University of Michigan reveal how well drug additives stop the active ingredients from crystallizing in the digestive tract. They tested these simulations on the anti-seizure drug phenytoin.

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‘5-D protein fingerprinting’ could give insights into Alzheimer’s, Parkinson’s

ANN ARBOR—In research that could one day lead to advances against neurodegenerative diseases like Alzheimer’s and Parkinson’s, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid. Proteins are essential to the function of every cell. Measuring their properties in blood and other […]

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$3.46M to Combine Supercomputer Simulations with Big Data

A new way of computing could lead to immediate advances in aerodynamics, climate science, cosmology, materials science and cardiovascular research …

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