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Jon-Fredrik Nielsen, Ph.D.

Research Associate Professor, Biomedical Engineering

Location

1067 BIRB
2360 Bonisteel Blvd
Ann Arbor, MI 48109-2108

Additional Title(s)

Research Associate Professor, Radiology

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Personal Profile

Education

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Biography

Dr. Nielsen has made significant experimental and applied contributions to magnetic resonance imaging (MRI) techniques. His current research focuses on three areas: (1) Enabling large-scale functional MRI research, independent of individual scanner manufacturer specifications. Dr. Nielsen co-developed Pulseq, an open-source pulse sequence specification, and associated platform-specific drivers, and he co-leads an international research effort using this framework. The aim is to harmonize data acquisition, reconstruction, and analysis to improve reproducibility of fMRI measures. (2) He co-led development of new “shaped” radiofrequency excitation pulses that offer greater flexibility in experimental design. He is investigating use of these pulses in 3D fMRI and other applications. (3) In collaboration with faculty from EECS, Radiology, and the Michigan Alzheimer’s Disease Center, Dr. Nielsen is correlating high-resolution MRI with histopathology to introduce a novel imaging biomarker for diagnosis and staging of Alzheimer’s disease.

Awards