Grace Bushnell’s Abstract: In most types of cancer, the formation of distant metastasis is the point at which the disease becomeslethal. At present, there is no clinical method to detect metastatic
Grace Bushnell’s Abstract:
In most types of cancer, the formation of distant metastasis is the point at which the disease becomeslethal. At present, there is no clinical method to detect metastatic dissemination and colonization of distal sites until radiologically evident, at which point the function of the organ has often already beencompromised. The Shea lab has developed a biomaterial implant that recruits metastatic cancer cells inxenogeneic human and syngeneic mouse models of breast cancer. Scaffold implantation has facilitateddetection of metastasis prior to colonization of organs and has been shown to reduce metastatic diseaseburden, ultimately resulting in enhanced survival with surgical intervention. Biomaterial scaffolds capable of recruiting metastatic tumor cells in vivo represent a transformative approach that can not only to serve as a platform for early detection and intervention, but also serves as a defined site in vivo to study metastasis.
The goal of the BME student speaker series is to allow students to improve their presentation and speaking skills in a relatively stress-free environment. Students typically present for 15-20 minutes, followed by a 5 min Q/A session. Students and faculty from BME and those with research affiliated with BME are welcome to attend and present. We still have open spots for this semester. If you are interested, please email me and use this link to sign up to present: http://goo.gl/2NJdnX
(Monday) 12:00 pm - 1:00 pm